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MOTS-c vs NAD+: Mechanism and Cost per mg

MOTS-c and NAD+ both show up in mitochondrial and longevity research, but they are not the same kind of molecule at all. One is a peptide, the other is a coenzyme.

MOTS-c

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Cost per milligram

Both are priced by the milligram, so you can compare what you actually pay, not just the sticker price.

$2.90
per mg
$0.08
per mg
MOTS-cNAD+
Molecule typeMitochondrial-derived peptideCoenzyme (dinucleotide)
OriginEncoded in mitochondrial DNA (12S rRNA)Synthesized from NAD precursors
Primary pathway studiedAMPK and metabolic homeostasisRedox reactions, sirtuin and PARP activity
ClassSignaling peptideCellular cofactor

MOTS-c is a mitochondrial-derived peptide, a short peptide encoded within mitochondrial DNA. Its studied mechanism centers on AMPK and metabolic homeostasis signaling.

NAD+ is not a peptide at all. It is a coenzyme (nicotinamide adenine dinucleotide) that sits at the center of cellular redox reactions and is a substrate for sirtuin and PARP enzymes.

So this is a comparison of two different molecule classes that happen to overlap in mitochondrial and longevity research, a signaling peptide on one side and a fundamental cellular cofactor on the other.

This compares molecular mechanism and receptor class from the published literature only, not efficacy, potency, or outcomes. All Boulder Labs products are for laboratory research use only. Not for human consumption.

Common questions

What is the difference between MOTS-c and NAD+?

MOTS-c is a mitochondrial-derived signaling peptide studied around AMPK and metabolic homeostasis. NAD+ is a coenzyme central to redox reactions and sirtuin and PARP activity. They are different classes of molecule that overlap in mitochondrial research.

How much do MOTS-c and NAD+ cost?

Both are priced by the milligram. The live cost per mg for each is shown above and on each product page, so you can compare the real per-mg cost directly.

MOTS-c researchNAD+ researchPrice per mg